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PERSONALIZED SUPPORT FOR PATIENTS AND FAMILIES

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Support specialists help you manage the challenges of living with LEMS

Patients with Lambert-Eaton myasthenic syndrome (LEMS) and their families face a variety of challenges every day. That’s why Catalyst Pathways® features a dedicated team of support specialists who have the answers you’re looking for and are trained to troubleshoot any issues that may arise.

Couple Sitting

Care Coordinator

Provides a warm welcome, passes along need-to-know info, and connects you to your dedicated team

Insurance Navigator

Handles complicated coverage and reimbursement issues and works to resolve them

Patient Access Liaison

Your go-to, local resource for education and treatment support when and where you need it

ENROLL NOW

Complete the Enrollment Form with your doctor or call 1-833-4-CATALYST
(1-833-422-8259) for assistance.

Enroll

The My FIRDAPSE Therapeutic Dose Program is designed to help you and your doctor determine the FIRDAPSE dose that will safely provide optimal relief of your LEMS symptoms while minimizing medication side effects.

Go to YourCatalystPathways.com for a full list of the support programs available, including financial assistance.

Talking to your doctor

Preparation is the key to having a productive conversation with your LEMS physician. You’ll want to start taking notes about how you’re feeling so that you can provide input to the doctor during your office visit. Your physician knows best when it comes to LEMS diagnosis and treatment, but when it comes to your symptoms, you are the expert! Your notes don’t need to be lengthy but should provide enough detail to give your doctor a clear picture of what’s going on.

Be sure to include:

  • Specific information about your symptoms and how they affect your daily activities
  • A timeline of your illness: when symptoms first appeared, how they progressed, and whether they’ve fluctuated, gotten better, or gotten worse
  • Details about previous treatments you’ve received or used, including prescription drugs, over-the-counter remedies, and any physical therapy or rehab
  • A list of any questions you have. It’s easy to forget your questions for the doctor when you’re in the exam room. Make a list and carry it with you into the exam—that way, you won’t forget to get the answers you’re looking for

Listen to Tom describe his personal experience with Catalyst Pathways

Mary Ann Talking
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"CATALYST HAS CHECKED UP WITH ME MONTHLY. THEY WERE SO KIND; THEY WERE SO COMFORTING. THEY WIPED OUT A LOT OF FEAR."

— Tom, Living with LEMS,
thriving with Catalyst Pathways

Share your story!

Do you have LEMS? Are you taking FIRDAPSE? Chances are, you've learned some things that might be helpful to someone newly diagnosed with LEMS.

Click on the email link below to share your experiences, thoughts, knowledge, and tips about your life with LEMS now.

advocacy@catalystpharma.com

Educational resources from FIRDAPSE

Take advantage of these resources available to patients with LEMS and their caregivers.

Patient Brochure

Move Forward with FIRDAPSE

This educational brochure provides easy-to-understand information about the causes of LEMS, its key symptoms, and how it’s diagnosed. It also includes information about FIRDAPSE, such as dosing tips, clinical study highlights, and details about our Delivery Assurance Program. The brochure closes with Important Safety Information, but not before you get to meet Wade and Jerry—two LEMS patients who found their way forward with FIRDAPSE.

Download
Patient Infographic

Could It Be LEMS?

This educational infographic illustrates the symptoms of LEMS as well as two forms of myasthenia gravis (MG)—disorders that are often mistaken for LEMS. The infographic shows how the disorders are similar but also points out key differences that may help you distinguish LEMS from MG.

Download
My Health Journal cover

My Health Journal

This treatment journal provides healthful lifestyle tips and journal pages where patients can easily track important information, such as their FIRDAPSE dosing schedule, other medications and supplements they are taking, and their response to treatment. Because LEMS symptoms can change or worsen over time, it’s important to keep an accurate record of your health status. Your doctor can use this information to make dose adjustments that can keep you at your best. To get a copy of the journal, call Catalyst Pathways at 1-833-422-8259 or talk to your Patient Access Liaison (PAL).

Mentor Program graphic

LEMS Connection

This mentoring program enables patients who have been diagnosed with LEMS to talk with other LEMS patients about their personal experiences with LEMS and/or FIRDAPSE. To get connected to a mentor, call 1-833-492-8853.

Patient Webinar

A Look at LEMS

This on-demand educational webinar allows patients to learn more about LEMS from a neuromuscular specialist, hear the personal journey of a woman living with LEMS, and find opportunities for support.

Watch this webinar now.
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CONTACT A CARE COORDINATOR

Call 1-833-4-CATALYST
(1-833-422-8259),
Monday-Friday, 7AM-7PM CST.
Visit YourCatalystPathways.com
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THANK YOU!

We’ll be in touch soon.

What is FIRDAPSE®?

FIRDAPSE is a prescription medicine used to treat adults 17 years of age or older with Lambert-Eaton myasthenic syndrome (LEMS). The safety and efficacy of FIRDAPSE in patients under the age of 17 has not been established.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about FIRDAPSE?

  • FIRDAPSE can cause seizures.
    • You could have a seizure even if you never had a seizure before.
    • Do not take FIRDAPSE if you have ever had a seizure.

Stop taking FIRDAPSE and call your doctor right away if you have a seizure while taking FIRDAPSE.

Do not take FIRDAPSE if you:

  • have ever had a seizure.
  • are allergic to amifampridine phosphate, or another aminopyridine.

Before you take FIRDAPSE, tell your doctor about all of your medical conditions, including if you:

  • are taking another aminopyridine, such as compounded 3,4-diaminopyridine (3,4-DAP)
  • have had a seizure
  • have kidney problems
  • have liver problems
  • are pregnant or plan to become pregnant. It is not known if FIRDAPSE will harm your unborn baby. You and your doctor will decide if you should take FIRDAPSE while you are pregnant.
  • There is a registry for women who become pregnant during treatment with FIRDAPSE. The purpose of this registry is to collect information about your health and your baby’s health. Contact the registry as soon as you learn that you are pregnant, or ask your healthcare provider to contact for you by calling 855-212-5856 (toll free), contacting the Fax number 877-867-1874 (toll free), emailing the Pregnancy Coordinating Center at firdapsepregnancyregistry@ubc.com, or visiting the study website www.firdapsepregnancystudy.com.
  • are breastfeeding or plan to breastfeed. It is not known if FIRDAPSE passes into your breast milk. Talk to your doctor about the best way to feed your baby while taking FIRDAPSE.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How should I take FIRDAPSE?

  • Take FIRDAPSE exactly as your doctor tells you to take it. Do not change your dose of FIRDAPSE.
  • Do not take more than 2 tablets of FIRDAPSE at one time or more than 8 tablets of FIRDAPSE in a 24-hour period.
  • FIRDAPSE can be taken with or without food.
  • If you miss a dose of FIRDAPSE, skip that dose and take your next dose at your next scheduled dose time. Do not double your dose to make up the missed dose.
  • Do not take FIRDAPSE together with other medicines known to increase the risk of seizures.
  • If you take too much FIRDAPSE, call your doctor or go to the nearest hospital emergency room right away.

What are the possible side effects of FIRDAPSE?

FIRDAPSE may cause serious side effects, including:

  • Seizures. See "What is the most important information I should know about FIRDAPSE?"
  • Serious allergic reactions, such as anaphylaxis. FIRDAPSE can cause serious allergic reactions. Stop taking FIRDAPSE and call your doctor right away or get emergency medical help if you have:
    • shortness of breath or trouble breathing
    • swelling of your throat or tongue
    • ­hives
  • The most common side effects of FIRDAPSE include:
    • tingling around the mouth, tongue, face, fingers, toes, and other body parts
    • upper respiratory infection
    • stomach pain
    • nausea
    • diarrhea
    • headache
    • increased liver enzymes
    • back pain
    • high blood pressure
    • muscle spasms

Tell your doctor if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of FIRDAPSE.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

How should I store FIRDAPSE?

  • Store FIRDAPSE at 68ºF to 77ºF (20ºC to 25ºC).
  • Safely throw away FIRDAPSE that is out of date or no longer needed.

Keep FIRDAPSE and all medicines out of the reach of children.

If you would like more information, ask your doctor or pharmacist for additional information about FIRDAPSE.

The active ingredient in FIRDAPSE is amifampridine phosphate. Inactive ingredients are calcium stearate, colloidal silicon dioxide, and microcrystalline cellulose.

Please see full Prescribing Information for additional Important Safety Information.

What is FIRDAPSE®?

FIRDAPSE is a prescription medicine used to treat adults 17 years of age or older with Lambert-Eaton myasthenic syndrome (LEMS). The safety and efficacy of FIRDAPSE in patients under the age of 17 has not been established.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about FIRDAPSE?

  • FIRDAPSE can cause seizures.
    • You could have a seizure even if you never had a seizure before.
    • Do not take FIRDAPSE if you have ever had a seizure.

Stop taking FIRDAPSE and call your doctor right away if you have a seizure while taking FIRDAPSE.

Do not take FIRDAPSE if you:

  • have ever had a seizure.
  • are allergic to amifampridine phosphate, or another aminopyridine.

Before you take FIRDAPSE, tell your doctor about all of your medical conditions, including if you:

  • are taking another aminopyridine, such as compounded 3,4-diaminopyridine (3,4-DAP)
  • have had a seizure
  • have kidney problems
  • have liver problems
  • are pregnant or plan to become pregnant. It is not known if FIRDAPSE will harm your unborn baby. You and your doctor will decide if you should take FIRDAPSE while you are pregnant.
  • There is a registry for women who become pregnant during treatment with FIRDAPSE. The purpose of this registry is to collect information about your health and your baby’s health. Contact the registry as soon as you learn that you are pregnant, or ask your healthcare provider to contact for you by calling 855-212-5856 (toll free), contacting the Fax number 877-867-1874 (toll free), emailing the Pregnancy Coordinating Center at firdapsepregnancyregistry@ubc.com, or visiting the study website www.firdapsepregnancystudy.com.
  • are breastfeeding or plan to breastfeed. It is not known if FIRDAPSE passes into your breast milk. Talk to your doctor about the best way to feed your baby while taking FIRDAPSE.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How should I take FIRDAPSE?

  • Take FIRDAPSE exactly as your doctor tells you to take it. Do not change your dose of FIRDAPSE.
  • Do not take more than 2 tablets of FIRDAPSE at one time or more than 8 tablets of FIRDAPSE in a 24-hour period.
  • FIRDAPSE can be taken with or without food.
  • If you miss a dose of FIRDAPSE, skip that dose and take your next dose at your next scheduled dose time. Do not double your dose to make up the missed dose.
  • Do not take FIRDAPSE together with other medicines known to increase the risk of seizures.
  • If you take too much FIRDAPSE, call your doctor or go to the nearest hospital emergency room right away.

What are the possible side effects of FIRDAPSE?

FIRDAPSE may cause serious side effects, including:

  • Seizures. See "What is the most important information I should know about FIRDAPSE?"
  • Serious allergic reactions, such as anaphylaxis. FIRDAPSE can cause serious allergic reactions. Stop taking FIRDAPSE and call your doctor right away or get emergency medical help if you have:
    • shortness of breath or trouble breathing
    • swelling of your throat or tongue
    • ­hives
  • The most common side effects of FIRDAPSE include:
    • tingling around the mouth, tongue, face, fingers, toes, and other body parts
    • upper respiratory infection
    • stomach pain
    • nausea
    • diarrhea
    • headache
    • increased liver enzymes
    • back pain
    • high blood pressure
    • muscle spasms

Tell your doctor if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of FIRDAPSE.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

How should I store FIRDAPSE?

  • Store FIRDAPSE at 68ºF to 77ºF (20ºC to 25ºC).
  • Safely throw away FIRDAPSE that is out of date or no longer needed.

Keep FIRDAPSE and all medicines out of the reach of children.

If you would like more information, ask your doctor or pharmacist for additional information about FIRDAPSE.

The active ingredient in FIRDAPSE is amifampridine phosphate. Inactive ingredients are calcium stearate, colloidal silicon dioxide, and microcrystalline cellulose.

Please see full Prescribing Information for additional Important Safety Information.

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